成都丽凯手性技术有限公司
Technology--Key Tech
Proficient Technology:
 Chiral resolution
 Asymmetric synthesis
 Oxidizing and reducing reactions
 Amination
 Esterification
 Catalyzing hydrogenation
 C, O, N-Alkylation
 Heterocyclic synthesis
Examples:
 Resolution: developing new methods of chemical resolution, crystal engineering.
"Combinatorial Approach" for the Choice of Resolving Reagents and Resolution of Chiral Drugs:
 
(R)-Albuterol with D-DBTA (>R)-Terbutaline with D-DTTA
Patent: ZL 01 1 07380.2, ZL 99 1 17313.9.
 Asymmetric synthesis: designing new chiral ligands and developing new asymmetric reactions.
Asymmetric Transfer Hydrogenation in Water
J. Org. Chem.2005, 70, 9424-9429; Org. Lett.2003, 5, 2103.
Patent: ZL 03135181.6
 New drug development:integrating chirotechnologies methodologies to develop new drugs.
Patent: ZL 98 1 24029.1, ZL 03 1 35146.6.